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Technologies Available for Licensing from NIH/FDA
Alpha 1-antitrypsin deficiency
| The UBE2G2 Binding Domain in the Ubiquitin Ligase GP78 and Methods of Use Thereof |
Cytosolic and nuclear proteins are targeted for proteosomal degradation by the addition of multiubiquitin chains. The specificity of this process is largely conferred by ubiquitin protein ligases (E3s) that interact with specific ubiquitin conjugating enzymes (E2s). One important role for ubiquitylation is in quality control in the secretory pathway, targeting proteins for degradation through a set of processes known as endoplasmic reticulum (E... More ...
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Technologies Available for Licensing from Non-Profit Institutions
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No external Non-Profit Institution Technology Abstracts are available for this Rare Disease/Condition. If you are a non-profit institution and would like to have your technology included in this list, please Click Here.
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